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Boost Your Energy & Immune System with Cortisol & Adrenaline | Episode 18

105 Min
Podcast
10 Favorites

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Andrew Huberman, Ph.D.
This episode I describe the biology of two essential hormones we all make: cortisol and adrenaline (also called epinephrine). Cortisol and adrenaline powerfully regulate our levels of energy, focus and immune system function. I describe various science-supported tools and practices to increase or decrease cortisol and/or adrenaline, depending on one's specific needs and goals. I also describe the biology of nootropics, and how cortisol and adrenaline can improve or degrade learning. Finally, I review the scientific data and tools for timing the release of these hormones to improve memory, energy and immune system function. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Thesis: https://takethesis.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Introduction (00:05:41) Energy & Your Immune System, & Learning Faster (00:08:34) Why & How Intermittent Fasting Increases Growth Hormone (00:11:56) Why Your Stomach Growls (00:13:09) Hot Baths & Hormones (00:14:35) Energy, Adrenaline (Epinephrine), & Cortisol (00:15:48) Cortisol & Cholesterol, Competition With Testosterone & Estrogen (00:17:54) Adrenaline (Epinephrine) Is Your (Immune Systems) Best Friend (00:18:48) Cortisol Basics In Two (Actually 1) Minute/s (00:19:48) Adrenaline Basics In Two Minutes (00:21:32) Tool: Time Your Cortisol Peak To Waking Using Specific Light Intensities (00:27:20) Brief Increases In Cortisol & Adrenaline Boost Energy, Focus & Immunity (00:30:04) Ways To Increase Adrenaline, Epinephrine & Cortisol & Why That Is Good (00:35:00) Does Mindset During Stress Matter? (00:36:15) Protocols: Adrenaline Breathing Described (00:39:00) Practices To Increase Energy Without Increasing Stress (00:45:00) Using Stressors to ENHANCE Our Immune System: Science & Tools (00:55:11) Timing Thyroid Release For Energy (00:57:02) Adrenaline/Stress Increase Performance & Memory. IF They Are After Learning (01:02:45) An Optimal Learning Protocol (01:03:20) Coffee Changes Your Brain & Increases Connectivity Of “Anxiety Circuits” (01:05:43) Nootropics: Two Kinds, & How & Why They Work, “Neural Energy” (01:09:00) Biology of Comfort Foods: From Negative to Positive Feedback Loops (01:14:00) Bombesin: Energy Without Eating (01:15:00) How Stress Makes Our Hair Gray, & How To Prevent Stress-Induced-Graying (01:18:05) Blunting Chronic Cortisol, Including: Ashwagandha & Science Of (01:25:50) Licorice Increases Cortisol & Blood Pressure, & Reduces Testosterone (by Glycyrrhizin) (01:28:50) Apigenin: Anti-Cortisol (01:29:53) Protocols For Optimizing Energy & Immune System Function (& Learning) (01:37:00) When Fasting, Exercise, Cold & Intense Breathing Become Detrimental (01:39:00) Prescription Compounds (01:39:47) Tools For Accessing Alert & Calm States of “Energy”: Separating The Brain & Body (01:42:11) Ways To Apply Knowledge Presented Today (01:43:20) No-Cost Ways To Support Us, Feedback, Sponsors, Patreon, Partners, “Office Hours” Title Card Photo Credit: Mike Blabac Disclaimer